Definitely, YES.
As the disorder progresses many individuals develop anxiety, spontaneous anger and appear to be aloof. Because of delusions, some individuals with schizophrenia do become violent in order to protect themselves from unknown threats. Both at work and at home, verbal confrontations are common often leading to disharmony and poor relationships. Many individuals with schizophrenia develop suicidal thoughts. Over time, the individuals become loners and tend to have difficulties at work and in interpersonal relationships. Unfortunately, all types of schizophrenia progress and without treatment, most individuals end up in health institutions or in legal difficulties.
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