Can you tell me what the major problem with schizophrenia is? My brother has it and we do understand what is happening?

One of the most misunderstood disorders in society is schizophrenia. While true estimates are lacking, it is believed that schizophrenia is present in 1/100 individuals. Schizophrenia often presents with a variety of mental symptoms including hallucinations, delusions and disordered thinking. Individuals who develop schizophrenia continue to get worse and over time are not able to take care of themselves. Despite what is widely believed, schizophrenia has nothing to do with multiple personalities. It is simply a disorder where one is not able to tell what is real and what is not. Individuals with schizophrenia generally do not harm others but only themselves. The paranoia can be so severe that most end up committing suicide. 

Despite intensive research, the disorder remains a puzzle and there is no ideal treatment. Schizophrenia has no cure and the only medications available only control the symptoms. No one really knows the cause of schizophrenia and this chronic disorder requires lifelong treatment.